Publikationen
Eine aktuelle Literaturliste der Mitarbeiter der Hautklinik Tübingen finden Sie in der Literatur-Datenbank PubMed.
Wichtige Publikationen
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, O'Day SJ, Sosman JA, Kirkwood JM, Eggermont AM, Dreno B, Nolop K, Li J, Nelson B, Hou J, Lee RJ, Flaherty KT, McArthur GA (2011) Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation. N Engl J Med
Robert C, Thomas L, Bondarenko I, O'Day S, M D JW, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD (2011) Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma. N Engl J Med
Schroeder BO, Wu Z, Nuding S, Groscurth S, Marcinowski M, Beisner J, Buchner J, Schaller M, Stange EF, Wehkamp J (2011) Reduction of disulfide bonds unmasks potent antimicrobial activity of human β-defensin 1. Nature 469, 419-423.
EINSTEIN investigators, Bauersachs R et al. (2010) Oral rivaroxaban for symptomatic ve-nous thromboembolism. N Engl J Med 363(26), 2499-510.
Hauschild A, Weichenthal M, Rass K, Linse R, Berking C, Böttjer J, Vogt T, Spieth K, Eigentler T, Brockmeyer NH, Stein A, Näher H, Schadendorf D, Mohr P, Kaatz M, Tronnier M, Hein R, Schuler G, Egberts F, Garbe C (2010) Efficacy of low-dose interferon {alpha}2a 18 versus 60 months of treatment in patients with primary melanoma of >= 1.5 mm tumor thickness: results of a randomized phase III DeCOG trial. J Clin Oncol 28(5), 841-6.
Kamenisch Y, Fousteri M, Knoch J, von Thaler AK, Fehrenbacher B, Kato H, Becker T, Dollé ME, Kuiper R, Majora M, Schaller M, van der Horst GT, van Steeg H, Röcken M, Rapaport D, Krutmann J, Mullenders LH, Berneburg M (2010) Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutane-ous fat, a hallmark of aging. J Exp Med 207(2), 379-90.
Maio M, Mackiewicz A, Testori A, Trefzer U, Ferraresi V, Jassem J, Garbe C, Lesimple T, Guillot B, Gascon P, Gilde K, Camerini R, Cognetti F; Thymosin Melanoma Investigation Group (2010) Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma. J Clin Oncol 28(5), 841-6.
Röcken M (2010) Early tumor dissemination, but late metastasis: insights into tumor dormancy. J Clin Invest 120,1800-3.
Hauschild A, Weichenthal M, Rass K, Linse R, Ulrich J, Stadler R, Volkenandt M, Grabbe S, Proske U, Schadendorf D, Brockmeyer N, Vogt T, Rompel R, Kaufmann R, Kaatz M, Näher H, Mohr P, Eigentler T, Livingstone E, Garbe C (2009) Prospective randomized multicenter adjuvant dermatologic cooperative oncology group trial of low-dose interferon alfa-2b with or without a modified high-dose interferon alfa-2b induction phase in patients with lymph node-negative melanoma. J Clin Oncol 28(10), 1780-7.
Kneilling M, Mailhammer R, Hültner L, Schönberger T, Fuchs K, Schaller M, Bukala D, Massberg S, Sander CA, Braumüller H, Eichner M, Maier KL, Hallmann R, Pichler BJ, Haubner R, Gawaz M, Pfeffer K, Biedermann T, Röcken M (2009) Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation. Blood 114(8), 1696-706.
Ziegler A, Heidenreich R, Braumuller H, Wolburg H, Weidemann S, Mocikat R, Rocken M (2009) EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion. Blood 2009 Apr 9; 113(15), 3494-502.
Brantsch K, Meisner C, Schönfisch B, Trilling B, Wehner-Caroli J, Röcken M, Breuninger H (2008) Prospective analysis of the risk factors determining prognosis of cutaneous squamous cell carcinoma. Lancet Oncology 9, 713-20.
Ghoreschi K, Thomas P, Penovici M, Ullmann J, Sander CA, Ledderose G, Plewig G, Kolb HJ, Röcken M (2008) PUVA-bath photochemotherapy and isotretinoin in sclerodermatous graft-versus-host disease. Eur J Dermatol 18(6), 667-70.
Gremmel T, Wild S, Schuller W, Kürten V, Dietz K, Krutmann J, Berneburg M (2008) Six genes associated with the clinical phenotypes of individuals with deficient and proficient DNA repair. Transl Oncogen 3, 1-13.
Judenhofer MS, Wehrl HF, Newprot DF, Catana C, Siegel SB, Becker M, Thielscher A, Kneilling M, Lichy M, Eichner M, Klingel K, Reischl G, Widmaier S, Röcken M, Nutt RE, Machulla HJ, Uludag K, Cherry SR, Claussen CD, Pichler BJ (2008) Simultaneous PET/MRI: a new approach for functional and morphological imaging Nature Med 14, 459-65.
Müller-Hermelink N, Braumüller H, Pichler B, Wieder T, Mailhammer R, Schaak K, Ghoreschi K, Yazdi A, Haubner R, Sander CA, Mocikat R, Schwaiger M, Förster I, Huss R, Weber WA, Kneilling M, Röcken M (2008) TNFR1- and IFN-y-signaling determine whether T cells induce tumor dormancy or promote multistage carcino genesis. Cancer Cell 13(6), 507-518.
Ulmer A, Beutel J, Süsskind D, Hilgers RD, Ziemssen F, Lüke M, Röcken M, Rohrbach M, Fierlbeck G, Bartz-Schmidt KU, Grisanti S (2008) Visualization of Circulating Melanoma Cells in Peripheral Blood of Patients with Primary Uveal Melanoma. Clin Cancer Res 14(14), 4469-4474.
Bodo E, Tobin DJ, Kamenisch Y, Biro T, Berneburg M, Funk W, Paus R (2007) Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy. Am J Pathol 171, 1153-1167.
Kneilling M, Hültner L, Pichler BJ, Mailhammer R, Morawietz L, Solomon S, Eichner M, Sabatino J, Biedermann T, Krenn V, Weber WA, Illges H, Haubner R, Röcken M (2007) Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice. Arthritis Rheum 56(6), 1806-16.
Lang PA, Schenck M, Nicolay JP, Becker JU, Kempe DS, Lupescu A, Koka S, Eisele K, Klarl BA, Rubben H, Schmid KW, Mann K, Hildenbrand S, Hefter H, Huber SM, Wieder T, Erhardt A, Haussinger D, Gulbins E, Lang F (2007) Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med. 13, 164-170.
Rebholz B, Haase I, Eckelt B, Paxian S, Flaig MJ, Ghoreschi K, Nedospasov SA, Mailhammer R, Debey-Pascher S, Schultze JL, Weindl G, Forster I, Huss R, Stratis A, Ruzicka T, Rocken M, Pfeffer K, Schmid RM, Rupec RA (2007) Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin. Immunity (27), 296-307.
Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting, HC, Schaller M (2007) Epithelial cells establish direct antifungal defense through Toll-like receptor 4-mediated signaling. J Clin Invest 12, 3664-3672.
Landi MT, Bauer J, Pfeiffer RM, Elder DE, Hulley B, Minghetti P, Calista D, Kanetsky PA, Pinkel D, Bastian BC (2006) MC1R germline variants confer risk for BRAF-mutant melanoma. Science 313(5786), 521-522.
Schaller M, Zakikhany K, Naglik JR, Weindl G, Hube B (2006) Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc 1, 2767-2773.
Schanz S, Ulmer A (2006) Medical mystery: gangrene and cutaneous nodules. N Engl J Med. 354(22), 2393-2394.
Meier F, Schittek B, Busch S, Garbe C, Smalley K, Satyamoorthy K, Li G, Herlyn M (2005) The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Front Biosci 10, 2986-3001. Review.
Schanz S, Schaefer J, Fierlbeck G (2005) Glucagonoma presenting with necrolytic migratory erythema: the Glucagonoma syndrome. Gastroenterology. 6, 1816, 2131.
Eigentler TK, Buettner PG, Leiter U, Garbe C (2004) Central Malignant Melanoma Registry of the German Dermatological Society. Impact of ulceration in stages I to III cutaneous melanoma as staged by the American Joint Committee on Cancer Staging System: an analysis of the German Central Malignant Melanoma Registry. J Clin Oncol 21, 4376-4383.
Herzinger T, Plewig G, Röcken M (2004) Use of sunscreens to protect against ultraviolet-induced lupus erythematosus. Arthritis Rheum 50(9):3045-6.
Leiter U, Buettner PG, Eigentler TK, Garbe C (2004) Prognostic factors of thin cutaneous melanoma: an analysis of the central malignant melanoma registry of the german dermatological society. J Clin Oncol 18, 3660-3667.
Schanz S, Fierlbeck G (2004) Images in clinical medicine. Scleromyxedema. N Engl J Med. 21, 2218.
Ghoreschi K, Thomas P, Breit S, Dugas M, Mailhammer R, van Eden W, van der Zee R, Biedermann T, Prinz J, Mack M, Mrowietz U, Christophers E, Schlondorff D, Plewig G, Sander CA, Rocken M (2003) Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease. Nat Med 9, 40-46.
Mocikat R, Braumuller H, Gumy A, Egeter O, Ziegler H, Reusch U, Bubeck A, Louis J, Mailhammer R, Riethmuller G, Koszinowski U, Rocken M (2003) Natural killer cells activated by MHC class Ilow targets prime dendritic cells to induce protective CD8 T cell responses. Immunity 19, 561-569.
Herzinger T, Schorling S, Röcken J, Röcken M (2002) A hoarse voice. Lancet 359(9314), 1308.
Röcken M, Hultner L (2002) Heavy functions for light chains. Nat Med 8, 668-670.
Schwarz A, Stander S, Berneburg M, Bohm M, Kulms D, van Steeg H, Grosse-Heitmeyer K, Krutmann J, Schwarz T (2002) Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair. Nat Cell Biol 4, 26-31.
Biedermann T, Zimmermann S, Himmelrich H, Gumy A, Egeter O, Sakrauski AK, Seegmüller I, Voigt H, Launois P, Levine AD, Wagner H, Heeg K, Louis JA, Röcken M (2001) Interleukin 4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice. Nat Immunol 2, 1054-1060.
Broughton BC, Berneburg M, Fawcett H, Taylor EM, Arlett CF, Nardo T, Stefanini M, Menefee E, Price VH, Queille S, Sarasin A, Bohnert E, Krutmann J, Davidson R, Kraemer KH, Lehmann AR (2001) Two individuals with features of both xeroderma pigmentosum and trichothiodystrophy highlight the complexity of the clinical outcomes of mutations in the XPD gene. Hum Mol Genet 2001 (10), 2539-2547.
Schittek B, Hipfel R, Sauer B, Bauer J, Kalbacher H, Stevanovic S, Schirle M, Schroeder K, Blin N, Meier F, Rassner G, Garbe C (2001) Dermcidin: a novel human antibiotic peptide secreted by sweat glands. Nat Immunol. 12, 1133-1137.
Berneburg M, Clingen P, Harcourt, SA, Lowe JE, Taylor EM, Green MHL, Krutmann J, Arlett CF, Lehmann AR (2000) The Cancer-free Phenotype in Trichothiodystrophy is Unrelated to its Repair Defect. Cancer Res 60, 431-438.
Berneburg M, Lowe JE, Nardo T, Araujo, Fousteri MI, Green M, Krutmann J, Wood RD, Stefanini M, Lehmann AR (2000) UV damage causes uncontrolled DNA breakage in cells from patients with combined features of XP-D and Cockayne Syndrome. EMBO J 19 (5), 1157-1166.
Biedermann T, Kneilling M, Mailhammer R, Meier K, Sander CA, Kollias G, Kunkel S, Hültner L, Röcken M (2000) Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2. J Exp Med 192, 1441-1452.
Egeter O, Mocikat R, Ghoreshi K, Dieckmann A, Röcken M (2000) Eradication of disseminated lymphoma with CpG DNA activated T cells from non-transgenic mice. Cancer Res 60, 1515-1520.
Rohrmus B, Thoma-Greber EM, Bogner JR, Röcken M (2000) Outlook in oral and cutaneous Kaposi’s Sarcoma. Lancet 356, 2160.
Lüftl M, Degitz K, Plewig G, Röcken M (1997) Psoralen bath plus UV-A therapy. Possibilities and limitations. Arch Dermatol 133(12), 1597-603.
Röcken M, Urban J, Shevach EM (1994) Antigen-specific activation, tolerization, and reactivation of the interleukin 4 pathway in vivo. J Exp Med 179(6), 1885-93.
Kerscher M, Volkenandt M, Meurer M, Lehmann P, Plewig G, Rocken M (1994) Treatment of localised scleroderma with PUVA bath photochemotherapy. Lancet 343, 1233 (letter).
Racke MK, Bonomo A, Scott DE, Cannella B, Levine A, Raine CS, Shevach EM, Röcken M (1994) Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med 180(5), 1961-6.
Röcken M, Müller KM, Saurat JH, Müller I, Louis JA, Cerottini JC, Hauser C (1992) Central role for TCR/CD3 ligation in the differentiation of CD4+T cells toward A Th1 or Th2 func-tional phenotype. J Immunol 148(1), 47-54.
Röcken M, Saurat JH, Hauser C (1992) A common precursor for CD4+ T cells producing IL-2 or IL-4. J Immunol 148(4), 1031-6.
Röcken M, Urban JF, Shevach EM (1992) Infection breaks T-cell tolerance. Nature 359, 79-82.
Vollenweider S, Saurat JH, Röcken M, Hauser C (1991) Evidence suggesting involvement of interleukin-4 (IL-4) production in spontaneous in vitro IgE synthesis in patients with atopic dermatitis. J Allgergy Clin Immunol 87(6), 1088-95.
Sollten Sie nicht direkt zum Suchergebnis geführt werden, kopieren Sie bitte die folgenden Suchkriterien komplett in die Suchmaske von PubMed .
Suchkriterien:
(rocken-m OR roecken-m) OR (garbe-c NOT weidner-w) OR (fierlbeck-g) OR (biedermann-t) OR (breuninger-h NOT laux-t NOT abb-j NOT Shaffer-TH) OR (schaller-m NOT schaller-mm NOT schaller-md NOT J-Pers-Soc-Psychol NOT lukacs-nw NOT Schaller-mf NOT schaller-mj NOT schaller-ml) OR (berneburg-m) OR (moehrle-m OR mohrle-m) OR (steins-a) OR (scherwitz-c) OR (schippert-w) OR (sonnichsen-K) OR (metzler-g) OR (rassner-g) OR (BAUER-J AND (BAHMER-F OR FARTASCH-M OR DIEPGEN-T OR LEITZ-G OR GARBE-C OR FIERLBECK-G OR BLUM-A OR BASTIAN-B OR BROSSART-P) NOT KOTTER-I)
